Medrano's Lancaster

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When you want delicious, authentic Mexican food, fast friendly service, the BEST margaritas, and a fun-filled atmosphere, come to Medrano's!!!

Currently open for indoor dining, outdoor dining, takeout, and delivery; ORDER NOW

Open 7 Days a Week

Hours

Sunday 9am -10pm

Monday - Thursday 11am -10pm

Friday - Saturday 11am - 11pm

Bar open late! 

Location Info

MEDRANO'S MEXICAN RESTAURANT LANCASTER

44276 10TH ST WEST

LANCASTER, CA 93534

661-948-4247

ORDER NOW.

Excluding some holidays and special events 

Wedding receptions, birthday parties, quinceaneras, holiday parties, meetings, retirement parties, memorials, 1st communions, comedy shows, etc...
If you want to impress your guests, have your next special event at Medrano’s Mexican Restaurant in Lancaster. With our large banquet room, delicious, authentic Mexican food, friendly experienced staff, and  affordable prices, your special event is sure to be a hit! 

We also cater! 661-948-4247 

The bar at Medrano's Lancaster is one of the busiest night hot spots in the Antelope Valley. We have a long happy hour with great food and drink specials, as well as dancing on Friday nights. During football season, you can join our Monday Night Football Club to watch the games with friends (and rivals) and get additional members' only specials throughout the week. Check out our Cinco de Mayo and St. Patrick's Day events, Super Bowl watch party, Halloween Bash/Costume Contest, Valentine's Day dancing, and our incredibly crazy all ages New Year's Eve celebration!