About Medrano's

We are a family owned and operated Mexican restaurant chain in Southern California with four locations to serve you: LancasterWest Palmdale, Quartz Hill, and Santa Clarita. Each of our locations offers delicious, authentic Mexican food, great drinks, fast friendly service, and guaranteed satisfaction.
You'll find all your favorite Mexican foods such as tacos, burritos, enchiladas, fajitas, carne asada, arroz con pollo, chile verde, taquitos, ceviche and more on our menus.
People love our tasty Margaritas; we make about 12 different flavors including the wildly popular Cadillac Maggie! We also serve a wide variety of domestic and imported beers, classic drinks like Tequila Sunrise and Piña Colada, Martinis, and popular cocktails like Scooby Snack and Blue Sky. Enjoy them during Happy Hour, karaoke or whenever!
The Restaurants
Each location has a large dining area and bar. The dining areas can accommodate a table for one as well as big groups. Along with great food and drinks, you can enjoy live sporting events on our large flat screen TV's in the dining rooms and bars.
Parts of the dining area or bar can be reserved for large parties per manager's discretion. In addition, our Lancaster location has a large, separate banquet area able to host more than 100 guests. It features meal options for almost every budget, a full bar, and plenty of room for a DJ and dancing!!
Our catering meal options are flexible. We offer large trays of food which are available for pickup or delivery. We can drop the food off at your location, or if you need a hand from our friendly, experienced servers, we will send as many as needed to help make your special event a success. Check out our banquets and catering page.
Satisfaction Guaranteed
We work hard to make sure you have the best experience at our restaurants. If you don't, please let us know. Before you go to Yelp, talk to one of our staff members.
We give back to the community. Our charitable giving has included fundraising help for schools, sports teams, churches and other non-profit organizations.
Contact us with questions or to learn more.

Our Story

In the year 1999, six brothers from Guanajuato, Mexico were all working at restaurants in Southern California. That same year, these six Medrano brothers: Francisco, Jose, Jesus, Jorge, Ramiro, and Zorro decided they would open their own restaurant. The idea for Medrano’s Mexican Restaurant was born!

With a focus on providing the best food and superior service, we opened Mexican Restaurant in Lancaster in 1999. After much success and growing popularity, we opened our East Palmdale location in 2003. We didn't stop there and opened the doors to our Quartz Hill location in 2010.

In 2015, we closed the doors to our East Palmdale location. That same year, we made a big move and opened our extremely popular West Palmdale location on Restaurant Row near the Antelope Valley Mall.

We opened the doors to our newest location in Santa Clarita/Canyon Country in July 2018. It is our first location outside of the Antelope Valley.

Making you feel at home while eating a delicious meal, having drinks, watching a game, or singing karaoke with friends and family is how we built our business, and it is why we continue to grow. We only hire service-oriented workers, and then we instill in them our service expectations - give EVERYONE the VIP treatment!

Visit Medrano's! You'll be glad you did.