NACHOS - Cheese
a bunch of stuff on it

Picture of a Medrano's big, wet burrito

What's Happening?

Happy Hour

Daily 1pm -  7:45pm
excluding holidays and special events

Sunday Brunch Buffet

Sundays 9am - 3pm
Complimentary Mimosas

Wednesday Lunch Buffet

11am - 2pm

Wednesday Senior Discounts

20% off food, ages 55 and up

Tuesday Military Discounts

20% off food, active and veterans


Tuesday 7pm - 10pm
Thursday 7pm - 10pm
Friday 9pm - 1am
Saturday 9pm - 1am

Picture of red, yelow and orange margaritas

After Hours Night Life

The bar at our Lancaster location is one of the busiest night hot spots in the Antelope Valley. We have a long happy hour with great food and drink specials. During football season, you can join our Monday Night Football Club to watch the games with friends (and rivals) and get additional members' only specials throughout the week. You can also join in the fun for our huge Cinco de Mayo and St. Patrick's Day events, Super Bowl viewing Party, Halloween Bash/Costume Contest, and our incredibly crazy all ages New Year's Eve celebration.

Our most popular attraction is our weekly karaoke. The singers are awesome, and the crowd is fun! Grab the mic and sing a tune, or sit back and sing along!!

image of our mural at the entrance of Medrano's Lancaster saying "Bienvenidos a Medrano's comida mexicana"

Hours and Location

Dining Room Hours

Sunday 9am - 10pm
Monday - Thursday 11am - 10pm
Friday and Saturday 11am - 11pm

Bar Hours

Sunday 9am - 10pm
Monday - Thursday 11am - 10pm
Friday and Saturday 11am - 1am


Medrano's Mexican Restaurant Lancaster
44276 10th Street West
Lancaster, CA 93534
Near the intersection of Ave J and 10th St West

Image of Medrano's Lancaster banquet room set up for a wedding reception

Banquets & Catering

Wedding receptions, birthday parties, quinceaneras, holiday parties, meetings, retirement parties, memorials, 1st communions, comedy shows, etc...
If you want to impress your guests, have your next special event at Medrano’s Mexican Restaurant in Lancaster. With our large banquet room, delicious, authentic Mexican food, friendly experienced staff, and  affordable prices, your special event is sure to be a hit! We also cater! 661-948-4247

Contact us today!

Medrano's Lancaster Sunday brunch buffet flyer, complimentary mimosas. Call 6619484247 for details

Sunday Brunch Buffet

Enjoy a family meal without breaking your budget at our ALL YOU CAN EAT Sunday Brunch Buffet, every Sunday from 9am - 3pm at our Lancaster location. Delicious, traditional Mexican entrées like enchiladas, burritos, carne asada, tacos, chile verde and arroz con pollo, fruit and salad bars, freshly made pancakes and omelets, handmade tortillas and complimentary Mimosas (limit 5 per customer)...  Only $16.95 per adult, $8.95 per child (10 and younger). Prices and food subject to change without notice.

Our Specials in Lancaster